รศ. ดร. สุพรรณ ฟู่เจริญ
Assoc.Prof.Supan Fucharoen

Qualification:

• วท.บ. (เทคนิคการแพทย์)
• วท.ม. (ชีวเคมี)
• ปริญญาเอก D.Sc. Molecular Biology
• Certificate molecular analysis Thalassemia and other disorder of blood

E-mail : supan@kku.ac.th
Professorship: • Associate Professor
• ผู้อำนวยการศูนย์วิจัยและพัฒนาการตรวจวินิจฉัยทางห้องปฏิบัติการทางการแพทย์ ( ศวป.)
Research interest :

• Thalassemia and related disorders

Publication :

ผลงานวิจัย

  • Tungwiwat W, Fucharoen G, Fucharoen S, Ratanasiri T, Sanchaisuriya K, Sae-Ung N. Application of maternal plasma DNA analysis for noninvasive prenatal diagnosis of Hb E-beta-thalassemia. Transl Res. 2007 Nov;150(5):319-25. Epub 2007 Jul 18.
  • Chaisue C, Kitcharoen S, Wilairat P, Jetsrisuparb A, Fucharoen G, Fucharoen S. alpha/beta-Globin mRNA ratio determination by multiplex quantitative real-time reverse transcription-polymerase chain reaction as an indicator of globin gene function. Clin Biochem. 2007 Aug 15; [Epub ahead of print]
  • Ratanasiri T, Charoenthong C, Komwilaisak R, Changtrakul Y, Fucharoen S, Wongkham J, Kleebkaow P, Seejorn K. Prenatal prevention for severe thalassemia disease at Srinagarind Hospital. J Med Assoc Thai. 2006 Oct;89 Suppl 4:S87-93.
  • Yamsri S, Sanchaisuriya K, Fucharoen S, Fucharoen G, Jetsrisuparb A, Wiangnon S, Changtrakul Y, Sanchaisuriya P. H63D mutation of the hemochromatosis gene and serum ferritin levels in Thai thalassemia carriers. Acta Haematol. 2007;118(2):99-105. Epub 2007 Jul 18.
  • Singsanan S, Fucharoen G, Savongsy O, Sanchaisuriya K, Fucharoen S. Molecular characterization and origins of Hb Constant Spring and Hb Paks? in Southeast Asian populations. Ann Hematol. 2007 Sep;86(9):665-9. Epub 2007 Jun 23.
  • Fucharoen S, Fucharoen G, Sae-ung N, Sanchaisuriya K. Thalassemia intermedia associated with the Hb Constant Spring EE Bart's disease in pregnancy: a molecular and hematological analysis. Blood Cells Mol Dis. 2007 Sep-Oct;39(2):195-8. Epub 2007 Jun 22.
  • Siriratmanawong N, Pinmuang-Ngam C, Fucharoen G, Fucharoen S. Prenatal diagnosis of Hb Bart's hydrops fetalis caused by a genetic compound heterozygosity for two different alpha-thalassemia determinants. Fetal Diagn Ther. 2007;22(4):264-8. Epub 2007 Mar 16.
  • Sanchaisuriya K, Fucharoen S, Ratanasiri T, Sanchaisuriya P, Fucharoen G, Dietz E, Schelp FP. Effect of the maternal betaE-globin gene on hematologic responses to iron supplementation during pregnancy. Am J Clin Nutr. 2007 Feb;85(2):474-9.
  • Tungwiwat W, Fucharoen S, Fucharoen G, Ratanasiri T, Sanchaisuriya K. Development and application of a real-time quantitative PCR for prenatal detection of fetal alpha(0)-thalassemia from maternal plasma. Ann N Y Acad Sci. 2006 Sep;1075:103-7.
  • Sae-ung N, Fucharoen G, Sanchaisuriya K, Fucharoen S. Alpha(0)-thalassemia and related disorders in northeast Thailand: a molecular and hematological characterization. Acta Haematol. 2007;117(2):78-82. Epub 2006 Nov 9.
  • Fucharoen G, Fucharoen S, Singsanan S, Sanchaisuriya K. Coexistence of Southeast Asian ovalocytosis and beta-thalassemia: a molecular and hematological analysis. Am J Hematol. 2007 May;82(5):381-5.
  • Fucharoen S, Singsanan S, Hama A, Fucharoen G, Sanchaisuriya K. Rapid molecular characterization of Hb Queens and Hb Siam: two variants easily misidentified as sickle Hb. Clin Biochem. 2007 Jan;40(1-2):137-40. Epub 2006 Aug 30.
  • Sanchaisuriya K, Fucharoen S, Ratanasiri T, Sanchaisuriya P, Fucharoen G, Dietz E, Schelp FP. Thalassemia and hemoglobinopathies rather than iron deficiency are major causes of pregnancy-related anemia in northeast Thailand. Blood Cells Mol Dis. 2006 Jul-Aug;37(1):8-11. Epub 2006 Jun 5.
  • Jetsrisuparb A, Sanchaisuriya K, Fucharoen G, Fucharoen S, Wiangnon S, Jetsrisuparb C, Sirijirachai J, Chansoong K. Development of severe anemia during fever episodes in patients with hemoglobin E trait and hemoglobin H disease combinations. J Pediatr Hematol Oncol. 2006 Apr;28(4):249-53.
  • Fucharoen G, Trithipsombat J, Sirithawee S, Yamsri S, Changtrakul Y, Sanchaisuriya K, Fucharoen S. Molecular and hematological profiles of hemoglobin EE disease with different forms of alpha-thalassemia. Ann Hematol. 2006 Jul;85(7):450-4. Epub 2006 Mar 25.
  • Fucharoen S, Panyasai S, Surapot S, Fucharoen G, Sanchaisuriya K. Compound heterozygote state for GgammaAgamma(deltabeta) degrees -thalassemia and hereditary persistence of fetal hemoglobin. Am J Hematol. 2005 Oct;80(2):119-23.
  • Fucharoen S, Fucharoen G, Sanchaisuriya K, Surapot S. Compound heterozygote states for Hb C/Hb Malay and Hb C/Hb E in pregnancy: a molecular and hematological analysis. Blood Cells Mol Dis. 2005 Sep-Oct;35(2):196-200.
  • Fucharoen S, Chunpanich S, Sanchaisuriya K, Fucharoen G, Kunyanone N. Thalassemia intermedia associated with complex interaction of Hb Beijing [alpha16(A14)Lys-->Asn] and Hb E [beta26(B8)Glu-->Lys] with a deletional alpha-thalassemia-1 in a Thai family. Hemoglobin. 2005;29(1):77-83.
  • Sanchaisuriya K, Fucharoen S, Fucharoen G, Ratanasiri T, Sanchaisuriya P, Changtrakul Y, Ukosanakarn U, Ussawaphark W, Schelp FP. A reliable screening protocol for thalassemia and hemoglobinopathies in pregnancy: an alternative approach to electronic blood cell counting. Am J Clin Pathol. 2005 Jan;123(1):113-8.
  • Chunpanich S, Fucharoen S, Sanchaisuriya K, Fucharoen G, Kam-itsara K. Molecular and hematological characterization of hemoglobin Hope/hemoglobin E and hemoglobin Hope/alpha-thalassemia 2 in Thai patients.Lab Hematol. 2004;10(4):215-20.
  • Sanchaisuriya K, Chunpanich S, Fucharoen S, Fucharoen G, Sanchaisuriya P, Changtrakun Y. Association of Hb Q-Thailand with homozygous Hb E and heterozygous Hb Constant Spring in pregnancy. Eur J Haematol. 2005 Mar;74(3):221-7.
  • Fucharoen G, Sanchaisuriya K, Sae-ung N, Dangwibul S, Fucharoen S. A simplified screening strategy for thalassaemia and haemoglobin E in rural communities in south-east Asia. Bull World Health Organ. 2004 May;82(5):364-72.
  • Panyasai S, Fucharoen S, Surapot S, Fucharoen G, Sanchaisuriya K. Molecular basis and hematologic characterization of deltabeta-thalassemia and hereditary persistence of fetal hemoglobin in Thailand. Haematologica. 2004 Jul;89(7):777-81.
  • Sanchaisuriya K, Chunpanich S, Fucharoen G, Fucharoen S. Multiplex allele-specific PCR assay for differential diagnosis of Hb S, Hb D-Punjab and Hb Tak. Clin Chim Acta. 2004 May;343(1-2):129-34.
  • Boonsa S, Sanchaisuriya K, Fucharoen G, Wiangnon S, Jetsrisuparb A, Fucharoen S. The diverse molecular basis and hematological features of Hb H and AEBart's diseases in Northeast Thailand. Acta Haematol. 2004;111(3):149-54.
  • Fucharoen S, Sanchaisuriya K, Fucharoen G, Panyasai S, Devenish R, Luy L. Interaction of hemoglobin E and several forms of alpha-thalassemia in Cambodian families. Haematologica. 2003 Oct;88(10):1092-8.
  • Yenchitsomanus PT, Sawasdee N, Paemanee A, Keskanokwong T, Vasuvattakul S, Bejrachandra S, Kunachiwa W, Fucharoen S, Jittphakdee P, Yindee W, Promwong C. Anion exchanger 1 mutations associated with distal renal tubular acidosis in the Thai population. J Hum Genet. 2003;48(9):451-6. Epub 2003 Aug 21.
  • Tungwiwat W, Fucharoen G, Ratanasiri T, Sanchaisuriya K, Fucharoen S. Non-invasive fetal sex determination using a conventional nested PCR analysis of fetal DNA in maternal plasma. Clin Chim Acta. 2003 Aug;334(1-2):173-7.
  • Laosombat V, Wiryyasateinkul A, Chrangtrakul Y, Fucharoen S. Rapid detection of an a thalassemia variant (Hb Quong Sze). Haematologica. 2003 Jul;88(7):ELT27. No abstract available.
  • Fucharoen G, Tungwiwat W, Ratanasiri T, Sanchaisuriya K, Fucharoen S. Prenatal detection of fetal hemoglobin E gene from maternal plasma. Prenat Diagn. 2003 May;23(5):393-6.
  • Fucharoen S, Changtrakun Y, Ratanasiri T, Fucharoen G, Sanchaisuriya K. Complex interaction of Hb Hekinan [alpha27(B8) Glu-Asp] and Hb E [beta26(B8) Glu-Lys] with a deletional alpha-thalassemia 1 in a Thai family. Eur J Haematol. 2003 May;70(5):304-9.
  • Fucharoen S, Changtrakun Y, Surapot S, Fucharoen G, Sanchaisuriya K. Molecular characterization of Hb D-Punjab [beta121(GH4)Glu-->Gln] in Thailand. Hemoglobin. 2002 Aug;26(3):261-9.
  • Sanchaisuriya K, Fucharoen G, Fucharoen S. Hb Paks? [(alpha2) codon 142 (TAA-->TAT or Term-->Tyr)J in Thai patients with EAbart's disease and Hb H Disease. Hemoglobin. 2002 Aug;26(3):227-35.
  • 34: Fucharoen S, Fucharoen G, Sanchaisuriya K, Surapot S. Molecular characterization of thalassemia intermedia associated with HPFH-6/beta-thalassemia and HPFH-6/Hb E in Thai patients. Acta Haematol. 2002;108(3):157-61.
  • Fucharoen S, Pengjam Y, Surapot S, Fucharoen G, Sanchaisuriya K. Molecular and hematological characterization of HPFH-6/Indian deletion-inversion Ggamma(Agammadeltabeta)0-thalassemia and Ggamma(Agammadeltabeta)0-thalassemia/HbE in Thai patients. Am J Hematol. 2002 Oct;71(2):109-13.
  • Panyasai S, Sringam P, Fucharoen G, Sanchaisuriya K, Fucharoen S. A simplified screening for alpha-thalassemia 1 (SEA type) using a combination of a modified osmotic fragility test and a direct PCR on whole blood cell lysates. Acta Haematol. 2002;108(2):74-8.
  • Fucharoen G, Fucharoen S, Sanchaisuriya K, Sae-Ung N, Suyasunanond U, Sriwilai P, Chinorak P. Frequency Distribution and Haplotypic Heterogeneity of beta(E)-Globin Gene among Eight Minority Groups of Northeast Thailand. Hum Hered. 2002;53(1):18-22.
  • Fucharoen S, Fucharoen G, Sanchaisuriya K, Pengjam Y. Molecular analysis of a thai beta-thalassaemia heterozygote with normal haemoglobin A2 level: implication for population screening. Ann Clin Biochem. 2002 Jan;39(Pt 1):44-9.
  • Jetsrisuparb A, Sanchaisuriya K, Fucharoen G, Fucharoen S, Wiangnon S, Komwilaisak P. Triple heterozygosity of a hemoglobin variant: hemoglobin Pyrgos with other hemoglobinopathies. Int J Hematol. 2002 Jan;75(1):35-9.
  • Tajima A, Pan IH, Fucharoen G, Fucharoen S, Matsuo M, Tokunaga K, Juji T, Hayami M, Omoto K, Horai S. Three major lineages of Asian Y chromosomes: implications for the peopling of east and southeast Asia. Hum Genet. 2002 Jan;110(1):80-8. Epub 2001 Nov 28.