Assoc.Prof.Supan Fucharoen

Education Degree

- D.Sc. Molecular Biology
- Certificate molecular analysis Thalassemia and other disorder of blood

Professorship:

Associate Professor
Director, Center for Research and Development of Medical Diagnostic Laboratories (CMDL)

E-mail :

supan@kku.ac.th

Research interest :

Thalassemia and related disorders

Publication :

1. Fetal hemoglobin in sickle cell anemia: genome-wide association studies suggest a regulatory region in the 5 olfactory receptor gene cluster. Solovieff N, Milton JN, Hartley SW, Sherva R, Sebastiani P, Dworkis DA, Klings ES, farrer LA, Garrett ME, Ashley-Koch A, Telen MJ, Fucharoen S, Ha SY, Li CK, Chui DHK, Baldwin CT, Steinberg MH. Blood (in press) doi:10.1182/blood-2009-08-239517.
2. Chaibunruang A, Srivorakun H, Fucharoen S, Fucharoen G, Sae-ung N, Sanchaisuriya K. Interactions of hemoglobin Lepore (db hybrid hemoglobin) with various hemoglobinopathies: a molecular and hematological characteristics and differential diagnosis. Blood Cells Mol Dis (in press)
3. Complex interaction of Hb E [b26(B8)Glu-Lys], Hb Korle-Bu [b73(E17)Asp-Asn] and a deletional a-thalassemia 1 in pregnancy. Siraratmanawong N, Chansri W, Singsanan S, Fucharoen G, Fucharoen S. Hemoglobin 2009; 33(6):507-514.
4. Accurate prenatal diagnosis of Hb Bart's hydrops fetalis in daily practice with a double-check PCR system.
Karnpean R, Fucharoen G, Fucharoen S, Sae-ung N, Sanchaisuriya K, Ratanasiri T. Acta Haematol. 2009;121(4):
227-33. Epub 2009 Jun 19.PMID: 19546525 [PubMed - indexed for MEDLINE]
Related articles

5. Analysis of fetal blood using capillary electrophoresis system: a simple method for prenatal diagnosis of severe thalassemia diseases. Srivorakun H, Fucharoen G, Sae-Ung N, Sanchaisuriya K, Ratanasiri T, Fucharoen S.
Eur J Haematol. 2009 Jul;83(1):57-65. Epub 2009 Feb 17.PMID: 19226360 [PubMed - indexed for MEDLINE]
Related articles
6. Accuracy of fetal gender detection using a conventional nested PCR assay of maternal plasma in daily practice.
Tungwiwat W, Fucharoen S, Fucharoen G, Ratanasiri T, Sanchaisuriya K. Aust N Z J Obstet Gynaecol. 2008 Oct;48(5):501-4.PMID: 19032667 [PubMed - indexed for MEDLINE]
Related articles

7. Hemoglobin profiles and hematologic features of thalassemic newborns: application to screening of alpha-thalassemia 1 and hemoglobin E. Tritipsombut J, Sanchaisuriya K, Fucharoen S, Fucharoen G, Siriratmanawong N, Pinmuang-ngam C, Sanchaisuriya P. Arch Pathol Lab Med. 2008 Nov;132(11):1739-45.PMID: 18976009 [PubMed - indexed for MEDLINE]
Related articles
8. Molecular, hematological and clinical aspects of thalassemia major and thalassemia intermedia associated with Hb E-beta-thalassemia in Northeast Thailand. Nuntakarn L, Fucharoen S, Fucharoen G, Sanchaisuriya K, Jetsrisuparb A, Wiangnon S. Blood Cells Mol Dis. 2009 Jan-Feb;42(1):32-5. Epub 2008 Oct 23.PMID: 18951049 [PubMed - indexed for MEDLINE]
Related articles
9. Effective screening for double heterozygosity of Hb E/alpha0-thalassemia.
Sanchaisuriya K, Chirakul S, Srivorakun H, Fucharoen G, Fucharoen S, Changtrakul Y, Sanchaisuriya P.
Ann Hematol. 2008 Nov;87(11):911-4. Epub 2008 Jun 25.PMID: 18575861 [PubMed - indexed for MEDLINE]
Related articles

10. Imputation of missing genotypes: an empirical evaluation of IMPUTE. Zhao Z, Timofeev N, Hartley SW, Chui DHK, Fucharoen S, Oerls TT, Steinberg MH, Baldwin CT, Sebastiani P. BMC Genetics 2008; 9:85 doi:10.1186/147-2156-9-85.
11. Application of maternal plasma DNA analysis for noninvasive prenatal diagnosis of Hb E-beta-thalassemia.
Tungwiwat W, Fucharoen G, Fucharoen S, Ratanasiri T, Sanchaisuriya K, Sae-Ung N.
Transl Res. 2007 Nov;150(5):319-25. Epub 2007 Jul 18.PMID: 17964521 [PubMed - indexed for MEDLINE]
Related articles
12. alpha/beta-Globin mRNA ratio determination by multiplex quantitative real-time reverse transcription-polymerase chain reaction as an indicator of globin gene function.
Chaisue C, Kitcharoen S, Wilairat P, Jetsrisuparb A, Fucharoen G, Fucharoen S.
Clin Biochem. 2007 Dec;40(18):1373-7. Epub 2007 Aug 15.PMID: 17920577 [PubMed - indexed for MEDLINE]
Related articles
13. Prenatal prevention for severe thalassemia disease at Srinagarind Hospital.
Ratanasiri T, Charoenthong C, Komwilaisak R, Changtrakul Y, Fucharoen S, Wongkham J, Kleebkaow P, Seejorn K.
J Med Assoc Thai. 2006 Oct;89 Suppl 4:S87-93.PMID: 17725145 [PubMed - indexed for MEDLINE]
Related articles
14. H63D mutation of the hemochromatosis gene and serum ferritin levels in Thai thalassemia carriers.
Yamsri S, Sanchaisuriya K, Fucharoen S, Fucharoen G, Jetsrisuparb A, Wiangnon S, Changtrakul Y, Sanchaisuriya P.
Acta Haematol. 2007;118(2):99-105. Epub 2007 Jul 18.PMID: 17637512 [PubMed - indexed for MEDLINE]
Related articles
15. Molecular characterization and origins of Hb Constant Spring and Hb Paks? in Southeast Asian populations.
Singsanan S, Fucharoen G, Savongsy O, Sanchaisuriya K, Fucharoen S. Ann Hematol. 2007 Sep;86(9):665-9. Epub 2007 Jun 23.PMID: 17589844 [PubMed - indexed for MEDLINE]
Related articles

16. Thalassemia intermedia associated with the Hb Constant Spring EE Bart's disease in pregnancy: a molecular and hematological analysis.
Fucharoen S, Fucharoen G, Sae-ung N, Sanchaisuriya K. Blood Cells Mol Dis. 2007 Sep-Oct;39(2):195-8. Epub 2007 Jun 22.PMID: 17587614 [PubMed - indexed for MEDLINE]
Related articles
17. Effect of the maternal betaE-globin gene on hematologic responses to iron supplementation during pregnancy.
Sanchaisuriya K, Fucharoen S, Ratanasiri T, Sanchaisuriya P, Fucharoen G, Dietz E, Schelp FP.
Am J Clin Nutr. 2007 Feb;85(2):474-9.PMID: 17284746 [PubMed - indexed for MEDLINE]
Related articles
Free article
18. Development and application of a real-time quantitative PCR for prenatal detection of fetal alpha(0)-thalassemia from maternal plasma.
Tungwiwat W, Fucharoen S, Fucharoen G, Ratanasiri T, Sanchaisuriya K. Ann N Y Acad Sci. 2006 Sep;1075:103-7.PMID: 17108198 [PubMed - indexed for MEDLINE]
Related articles

19. Alpha(0)-thalassemia and related disorders in northeast Thailand: a molecular and hematological characterization.
Sae-ung N, Fucharoen G, Sanchaisuriya K, Fucharoen S. Acta Haematol. 2007;117(2):78-82. Epub 2006 Nov 9.PMID: 17106191 [PubMed - indexed for MEDLINE]
Related articles
20. Coexistence of Southeast Asian ovalocytosis and beta-thalassemia: a molecular and hematological analysis.
Fucharoen G, Fucharoen S, Singsanan S, Sanchaisuriya K. Am J Hematol. 2007 May;82(5):381-5.PMID: 17094097 [PubMed - indexed for MEDLINE]
Related articles
21. Rapid molecular characterization of Hb Queens and Hb Siam: two variants easily misidentified as sickle Hb.
Fucharoen S, Singsanan S, Hama A, Fucharoen G, Sanchaisuriya K. Clin Biochem. 2007 Jan;40(1-2):137-40. Epub 2006 Aug 30.PMID: 17014836 [PubMed - indexed for MEDLINE]
Related articles
22. Thalassemia and hemoglobinopathies rather than iron deficiency are major causes of pregnancy-related anemia in northeast Thailand.
Sanchaisuriya K, Fucharoen S, Ratanasiri T, Sanchaisuriya P, Fucharoen G, Dietz E, Schelp FP.
Blood Cells Mol Dis. 2006 Jul-Aug;37(1):8-11. Epub 2006 Jun 5.PMID: 16750922 [PubMed - indexed for MEDLINE]
Related articles
23. Development of severe anemia during fever episodes in patients with hemoglobin E trait and hemoglobin H disease combinations.
Jetsrisuparb A, Sanchaisuriya K, Fucharoen G, Fucharoen S, Wiangnon S, Jetsrisuparb C, Sirijirachai J, Chansoong K.
J Pediatr Hematol Oncol. 2006 Apr;28(4):249-53.PMID: 16679924 [PubMed - indexed for MEDLINE]
Related articles

24. Molecular and hematological profiles of hemoglobin EE disease with different forms of alpha-thalassemia.
Fucharoen G, Trithipsombat J, Sirithawee S, Yamsri S, Changtrakul Y, Sanchaisuriya K, Fucharoen S.
Ann Hematol. 2006 Jul;85(7):450-4. Epub 2006 Mar 25.PMID: 16565831 [PubMed - indexed for MEDLINE]
Related articles

25. Compound heterozygote state for GgammaAgamma(deltabeta) degrees -thalassemia and hereditary persistence of fetal hemoglobin.
Fucharoen S, Panyasai S, Surapot S, Fucharoen G, Sanchaisuriya K. Am J Hematol. 2005 Oct;80(2):119-23.PMID: 16184575 [PubMed - indexed for MEDLINE]
Related articles
26. Compound heterozygote states for Hb C/Hb Malay and Hb C/Hb E in pregnancy: a molecular and hematological analysis.
Fucharoen S, Fucharoen G, Sanchaisuriya K, Surapot S. Blood Cells Mol Dis. 2005 Sep-Oct;35(2):196-200.PMID: 15982909 [PubMed - indexed for MEDLINE]
Related articles

27. Molecular and haematological characterization of compound Hb E/Hb Pyrgos and Hb E/Hb J-Bangkok in Thai patients.
Fucharoen S, Singsanan S, Sanchaisuriya K, Fucharoen G. Clin Lab Haematol. 2005 Jun;27(3):184-9.PMID: 15938724 [PubMed - indexed for MEDLINE]
Related articles
Free article
28. Thalassemia intermedia associated with complex interaction of Hb Beijing [alpha16(A14)Lys-->Asn] and Hb E [beta26(B8)Glu-->Lys] with a deletional alpha-thalassemia-1 in a Thai family.
Fucharoen S, Chunpanich S, Sanchaisuriya K, Fucharoen G, Kunyanone N. Hemoglobin. 2005;29(1):77-83.PMID: 15768559 [PubMed - indexed for MEDLINE]
Related articles

29. A reliable screening protocol for thalassemia and hemoglobinopathies in pregnancy: an alternative approach to electronic blood cell counting.
Sanchaisuriya K, Fucharoen S, Fucharoen G, Ratanasiri T, Sanchaisuriya P, Changtrakul Y, Ukosanakarn U, Ussawaphark W, Schelp FP.
Am J Clin Pathol. 2005 Jan;123(1):113-8.PMID: 15762286 [PubMed - indexed for MEDLINE]
Related articles
Free article
30. Molecular and hematological characterization of hemoglobin Hope/hemoglobin E and hemoglobin Hope/alpha-thalassemia 2 in Thai patients.
Chunpanich S, Fucharoen S, Sanchaisuriya K, Fucharoen G, Kam-itsara K. Lab Hematol. 2004;10(4):215-20.PMID: 15697092 [PubMed - indexed for MEDLINE]
Related articles

31. Association of Hb Q-Thailand with homozygous Hb E and heterozygous Hb Constant Spring in pregnancy.
Sanchaisuriya K, Chunpanich S, Fucharoen S, Fucharoen G, Sanchaisuriya P, Changtrakun Y.
Eur J Haematol. 2005 Mar;74(3):221-7.PMID: 15693792 [PubMed - indexed for MEDLINE]
Related articles

32. Laboratory diagnosis of a compound heterozygosity for Hb Hekinan [alpha27(B8) Glu-Asp] and a deletional alpha-thalassaemia 2 in Thailand.
Chunpanich S, Ayukarn K, Sanchaisuriya K, Fucharoen G, Fucharoen S. Clin Lab Haematol. 2004 Oct;26(5):355-8.PMID: 15485467 [PubMed - indexed for MEDLINE]
Related articles
Free article
33. A simplified screening strategy for thalassaemia and haemoglobin E in rural communities in south-east Asia.
Fucharoen G, Sanchaisuriya K, Sae-ung N, Dangwibul S, Fucharoen S. Bull World Health Organ. 2004 May;82(5):364-72.PMID: 15298227 [PubMed - indexed for MEDLINE]
Related articles
Free article
34. Molecular basis and hematologic characterization of deltabeta-thalassemia and hereditary persistence of fetal hemoglobin in Thailand.
Panyasai S, Fucharoen S, Surapot S, Fucharoen G, Sanchaisuriya K. Haematologica. 2004 Jul;89(7):777-81.PMID: 15257928 [PubMed - indexed for MEDLINE]
Related articles
Free article
35. Multiplex allele-specific PCR assay for differential diagnosis of Hb S, Hb D-Punjab and Hb Tak.
Sanchaisuriya K, Chunpanich S, Fucharoen G, Fucharoen S. Clin Chim Acta. 2004 May;343(1-2):129-34.PMID: 15115684 [PubMed - indexed for MEDLINE]
Related articles

36. The diverse molecular basis and hematological features of Hb H and AEBart's diseases in Northeast Thailand.
Boonsa S, Sanchaisuriya K, Fucharoen G, Wiangnon S, Jetsrisuparb A, Fucharoen S.
Acta Haematol. 2004;111(3):149-54.PMID: 15034236 [PubMed - indexed for MEDLINE]
Related articles

37. Interaction of hemoglobin E and several forms of alpha-thalassemia in Cambodian families.
Fucharoen S, Sanchaisuriya K, Fucharoen G, Panyasai S, Devenish R, Luy L.
Haematologica. 2003 Oct;88(10):1092-8.PMID: 14555303 [PubMed - indexed for MEDLINE]
Related articles
Free article
38. Molecular and hematologic features of hemoglobin E heterozygotes with different forms of alpha-thalassemia in Thailand.
Sanchaisuriya K, Fucharoen G, Sae-ung N, Jetsrisuparb A, Fucharoen S. Ann Hematol. 2003 Oct;82(10):612-6. Epub 2003 Aug 30.PMID: 12955472 [PubMed - indexed for MEDLINE]
Related articles

39. Non-invasive fetal sex determination using a conventional nested PCR analysis of fetal DNA in maternal plasma.
Tungwiwat W, Fucharoen G, Ratanasiri T, Sanchaisuriya K, Fucharoen S. Clin Chim Acta. 2003 Aug;334(1-2):173-7.PMID: 12867289 [PubMed - indexed for MEDLINE]
Related articles

40. Prenatal detection of fetal hemoglobin E gene from maternal plasma.
Fucharoen G, Tungwiwat W, Ratanasiri T, Sanchaisuriya K, Fucharoen S. Prenat Diagn. 2003 May;23(5):393-6.PMID: 12749037 [PubMed - indexed for MEDLINE]
Related articles
41. Complex interaction of Hb Hekinan [alpha27(B8) Glu-Asp] and Hb E [beta26(B8) Glu-Lys] with a deletional alpha-thalassemia 1 in a Thai family.
Fucharoen S, Changtrakun Y, Ratanasiri T, Fucharoen G, Sanchaisuriya K. Eur J Haematol. 2003 May;70(5):304-9.PMID: 12694166 [PubMed - indexed for MEDLINE]
Related articles

42. Molecular characterization of Hb D-Punjab [beta121(GH4)Glu-->Gln] in Thailand.
Fucharoen S, Changtrakun Y, Surapot S, Fucharoen G, Sanchaisuriya K. Hemoglobin. 2002 Aug;26(3):261-9.PMID: 12403491 [PubMed - indexed for MEDLINE]
Related articles
43. Hb Paks? [(alpha2) codon 142 (TAA-->TAT or Term-->Tyr)J in Thai patients with EAbart's disease and Hb H Disease.
Sanchaisuriya K, Fucharoen G, Fucharoen S. Hemoglobin. 2002 Aug;26(3):227-35.PMID: 12403487 [PubMed - indexed for MEDLINE]
Related articles
44. Molecular characterization of thalassemia intermedia associated with HPFH-6/beta-thalassemia and HPFH-6/Hb E in Thai patients.
Fucharoen S, Fucharoen G, Sanchaisuriya K, Surapot S. Acta Haematol. 2002;108(3):157-61.PMID: 12373089 [PubMed - indexed for MEDLINE]
Related articles

45. Molecular and hematological characterization of HPFH-6/Indian deletion-inversion Ggamma(Agammadeltabeta)0-thalassemia and Ggamma(Agammadeltabeta)0-thalassemia/HbE in Thai patients.
Fucharoen S, Pengjam Y, Surapot S, Fucharoen G, Sanchaisuriya K. Am J Hematol. 2002 Oct;71(2):109-13.PMID: 12353310 [PubMed - indexed for MEDLINE]
Related articles

46. A simplified screening for alpha-thalassemia 1 (SEA type) using a combination of a modified osmotic fragility test and a direct PCR on whole blood cell lysates.
Panyasai S, Sringam P, Fucharoen G, Sanchaisuriya K, Fucharoen S. Acta Haematol. 2002;108(2):74-8.PMID: 12187024 [PubMed - indexed for MEDLINE]
Related articles
47. Compound heterozygosity for Hb Korle-Bu (beta(73); Asp-Asn) and Hb E (beta(26); Glu-Lys) with a 3.7-kb deletional alpha-thalassemia in Thai patients.
Changtrakun Y, Fucharoen S, Ayukarn K, Siriratmanawong N, Fucharoen G, Sanchaisuriya K.
Ann Hematol. 2002 Jul;81(7):389-93. Epub 2002 Jul 3.PMID: 12185510 [PubMed - indexed for MEDLINE]
Related articles

48. Frequency Distribution and Haplotypic Heterogeneity of beta(E)-Globin Gene among Eight Minority Groups of Northeast Thailand.
Fucharoen G, Fucharoen S, Sanchaisuriya K, Sae-Ung N, Suyasunanond U, Sriwilai P, Chinorak P.
Hum Hered. 2002;53(1):18-22.PMID: 11901267 [PubMed - indexed for MEDLINE]
Related articlesFree article
49. Molecular characterization of (deltabeta)(0)/beta(0)-thalassemia and (deltabeta)(0)-thalassemia/hemoglobin E in Thai patients.
Fucharoen S, Pengjam Y, Surapot S, Fucharoen G, Sanchaisuriya K. Eur J Haematol. 2001 Oct;67(4):258-62.PMID: 11860449 [PubMed - indexed for MEDLINE]
Related articles

50. Molecular analysis of a thai beta-thalassaemia heterozygote with normal haemoglobin A2 level: implication for population screening.
Fucharoen S, Fucharoen G, Sanchaisuriya K, Pengjam Y. Ann Clin Biochem. 2002 Jan;39(Pt 1):44-9.PMID: 11853188 [PubMed - indexed for MEDLINE]
Related articles

51. Triple heterozygosity of a hemoglobin variant: hemoglobin Pyrgos with other hemoglobinopathies.
Jetsrisuparb A, Sanchaisuriya K, Fucharoen G, Fucharoen S, Wiangnon S, Komwilaisak P.
Int J Hematol. 2002 Jan;75(1):35-9.PMID: 11843288 [PubMed - indexed for MEDLINE]
Related articles

52. Simultaneous PCR detection of beta - thalassemia and alpha - thalassemia 1 (SEA type) in prenatal diagnosis of complex thalassemia syndrome.
Siriratmanawong N, Fucharoen G, Sanchaisuriya K, Ratanasiri T, Fucharoen S. Clin Biochem. 2001 Jul;34(5):377-80.PMID: 11522274 [PubMed - indexed for MEDLINE]
Related articles

53. Atypical hemoglobin H disease in a Thai patient resulting from a combination of alpha-thalassemia 1 and hemoglobin Constant Spring with hemoglobin J Bangkok heterozygosity.
Fucharoen S, Ayukarn K, Sanchaisuriya K, Fucharoen G. Eur J Haematol. 2001 May;66(5):312-6.PMID: 11422410 [PubMed - indexed for MEDLINE]
Related articles

54. Molecular characterization of hemoglobin C in Thailand.
Sanchaisuriya K, Fucharoen G, Sae-ung N, Siriratmanawong N, Surapot S, Fucharoen S.
Am J Hematol. 2001 Jul;67(3):189-93.PMID: 11391717 [PubMed - indexed for MEDLINE]
Related articles
55. Mitochondrial DNA polymorphisms in Thailand.
Fucharoen G, Fucharoen S, Horai S. J Hum Genet. 2001;46(3):115-25.PMID: 11310578 [PubMed - indexed for MEDLINE]
Related articles

56. Beta-globin gene haplotypes in some minor ethnic groups in Thailand.
Fucharoen G, Fucharoen S, Wilai Y, Chinoluck P, Khunsuk S, Sanchaisuriya K, Sae-ung N.
Southeast Asian J Trop Med Public Health. 1997;28 Suppl 3:115-9.PMID: 9640612 [PubMed - indexed for MEDLINE]
Related articles

57. Molecular and hematological characterization of Hb Tak and Hb Pyrgos in Thailand.
Fucharoen S, Fucharoen G, Sae-ung N, Sanchaisuriya K, Fukumaki Y.
Southeast Asian J Trop Med Public Health. 1997;28 Suppl 3:110-4.PMID: 9640611 [PubMed - indexed for MEDLINE]
Related articles
58. Molecular and hematological characterization of HbE heterozygote with alpha-thalassemia determinant.
Sanchaisuriya K, Fucharoen G, Sae-ung N, Sae-ue N, Baisungneon R, Jetsrisuparb A, Fucharoen S.
Southeast Asian J Trop Med Public Health. 1997;28 Suppl 3:100-3.PMID: 9640608 [PubMed - indexed for MEDLINE]
Related articles

59. A simple non radioactive method for detecting beta-thalassemia/hbe disease: application to prenatal diagnosis.
Fucharoen S, Fucharoen G, Ratanasiri T, Jetsrisuparb A, Fukumaki Y.
Southeast Asian J Trop Med Public Health. 1995;26 Suppl 1:278-81.PMID: 8629124 [PubMed - indexed for MEDLINE]
Related articles
60. Molecular basis of alpha (0)-thalassemia in northeast of Thailand.
Fucharoen G, Fucharoen S, Wanhakit C, Srithong W. Southeast Asian J Trop Med Public Health. 1995;26 Suppl 1:249-51.PMID: 8629116 [PubMed - indexed for MEDLINE]
Related articles

61. Expression of hemoglobin E in newborn.
Sae-ung N, Fucharoen G, Fucharoen S. Southeast Asian J Trop Med Public Health. 1995;26 Suppl 1:246-8.PMID: 8629115 [PubMed - indexed for MEDLINE]
Related articles

62. A simple non-radioactive assay for hemoglobin E gene in prenatal diagnosis.
Fucharoen S, Fucharoen G, Ratanasiri T, Jetsrisuparb A, Fukumaki Y.
Clin Chim Acta. 1994 Sep;229(1-2):197-203. No abstract available. PMID: 7988050 [PubMed - indexed for MEDLINE]
Related articles

63. Double heterozygosity of the beta-Malay and a novel beta-thalassemia gene in a Thai patient.
Fucharoen S, Fucharoen G, Laosombat V, Fukumaki Y. Am J Hematol. 1991 Oct;38(2):142-4.PMID: 1951306 [PubMed - indexed for MEDLINE]
Related articles

 

 



Faculty of Associated Medical Sciences Khon kaen University Tel : 0 4320 2399, 0 4334 7482 International Phone/Fax: +66 43 202399, +66 43 347482